Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15537592 | 0.92 | BRD4 (0.62) | BRD4EP300 | |
| SCHEMBL15541159 | 0.89 | BRD4 (0.62) | BRD4EP300 | |
| SCHEMBL15541497 | 0.88 | BRD4 (0.52) | BRD4EP300 | |
| SCHEMBL15537786 | 0.87 | BRD4 (0.64) | BRD4EP300 | |
| SCHEMBL15538083 | 0.87 | BRD4 (0.62) | BRD4EP300 | |
| SCHEMBL15538092 | 0.86 | BRD4 (0.65) | BRD4EP300 | |
| SCHEMBL15538589 | 0.85 | BRD4 (0.58) | BRD4EP300 | |
| SCHEMBL15537716 | 0.84 | BRD4 (0.52) | BRD4EP300 | |
| SCHEMBL15540255 | 0.84 | BRD4 (0.51) | BRD4EP300 | |
| SCHEMBL15538004 | 0.82 | BRD4 (0.64) | BRD4EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858982-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | AbbVie Inc. (US) | 2015-04-15 | — | — | EP | claimed |
| WO-2013185284-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | ABBOTT LABORATORIES (US) | 2013-12-19 | — | — | WO | claimed |
| EP-2858990-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | AbbVie Inc. (US) | 2015-04-15 | — | — | EP | disclosed |
| EP-2858982-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | AbbVie Inc. (US) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013188381-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | ABBVIE INC. (US) | 2013-12-19 | — | — | WO | disclosed |
| WO-2013185284-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | ABBOTT LABORATORIES (US) | 2013-12-19 | — | — | WO | disclosed |