Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 5/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | GYS1 | P13807 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15540010 | 1.00 | HCRTR1 (0.45) | HCRTR1HCRTR2PDK2SCN9ASPHK2 | |
| SCHEMBL15538559 | 1.00 | HCRTR1 (0.45) | HCRTR1HCRTR2PDK2SCN9ASPHK2 | |
| SCHEMBL15537896 | 0.97 | HCRTR1 (0.46) | HCRTR1HCRTR2PDK2SCN9ASPHK2 | |
| SCHEMBL15539219 | 0.97 | HCRTR1 (0.46) | HCRTR1HCRTR2PDK2SCN9ASPHK2 | |
| SCHEMBL15538442 | 0.97 | HCRTR1 (0.46) | HCRTR1HCRTR2PDK2SCN9ASPHK2 | |
| SCHEMBL15537988 | 0.92 | HCRTR1 (0.47) | HCRTR1HCRTR2GYS1 | |
| SCHEMBL15538030 | 0.92 | HCRTR1 (0.47) | HCRTR1HCRTR2GYS1 | |
| SCHEMBL15538728 | 0.92 | HCRTR1 (0.44) | HCRTR1HCRTR2PDK2SCN9ASPHK2 | |
| SCHEMBL15538731 | 0.92 | HCRTR1 (0.44) | HCRTR1HCRTR2PDK2SCN9ASPHK2 | |
| SCHEMBL15538578 | 0.91 | PDK2 (0.46) | HCRTR1HCRTR2PDK2CNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | claimed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | claimed |