Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 12/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 11/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | MTTP | P55157 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539019 | 1.00 | HCRTR1 (0.42) | HCRTR1HCRTR2PDK2HTR1AHTR7 | |
| SCHEMBL15539141 | 0.97 | PDK2 (0.42) | HCRTR1HCRTR2PDK2HTR1AHTR7 | |
| SCHEMBL15537935 | 0.91 | PDK2 (0.39) | HCRTR1HCRTR2PDK2HTR1AHTR7 | |
| SCHEMBL21534659 | 0.87 | PDK2 (0.41) | PDK2HTR1AHTR7DPP4 | |
| SCHEMBL16803775 | 0.87 | PDK2 (0.41) | PDK2HTR1AHTR7DPP4 | |
| SCHEMBL15538724 | 0.86 | HCRTR1 (0.40) | HCRTR1HCRTR2PDK2HTR1AHTR7 | |
| SCHEMBL15539668 | 0.86 | HCRTR1 (0.40) | HCRTR1HCRTR2PDK2HTR1AHTR7 | |
| SCHEMBL15539571 | 0.85 | HCRTR1 (0.39) | HCRTR1HCRTR2PDK2HTR1AHTR7 | |
| SCHEMBL15538442 | 0.85 | HCRTR1 (0.46) | HCRTR1HCRTR2PDK2SCN9A | |
| SCHEMBL15539219 | 0.85 | HCRTR1 (0.46) | HCRTR1HCRTR2PDK2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | claimed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | claimed |