Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.49 |
| ▸ | MAOA | P21397 | 6/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL15542079 | 1.00 | MAOB (0.49) | MAOBMAOAHTR2AHTR2CHTR2B | |
| SCHEMBL15540919 | 0.92 | MAOB (0.57) | MAOBMAOAHTR2AHTR2CHTR2B | |
| SCHEMBL6427142 | 0.92 | MAOB (0.57) | MAOBMAOAHTR2AHTR2CHTR2B | |
| SCHEMBL15542347 | 0.92 | MAOB (0.57) | MAOBMAOAHTR2AHTR2CHTR2B | |
| Trifluoroacetic Acid SCHEMBL15540515 | 0.83 | MAOB (0.71) | MAOBMAOAKDM1A | |
| Trifluoroacetic Acid SCHEMBL15542082 | 0.83 | MAOB (0.71) | MAOBMAOAKDM1A | |
| SCHEMBL301325 | 0.78 | MAOB (0.55) | MAOBMAOAHTR2AHTR2CHTR2B | |
| SCHEMBL2832287 | 0.76 | MAOB (0.59) | MAOBMAOAKMT2AKDM1A | |
| SCHEMBL5998895 | 0.71 | KMT2A (0.62) | MAOBMAOAKMT2A | |
| Trifluoroacetic Acid SCHEMBL15540543 | 0.69 | MAOB (0.44) | MAOBMAOAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867226-B1 | COMPLEMENT PATHWAY MODULATORS AND USES THEREOF | NOVARTIS AG (CH) | 2018-11-14 | — | — | EP | disclosed |
| EP-2867226-A2 | COMPLEMENT PATHWAY MODULATORS AND USES THEREOF | Novartis AG (CH) | 2015-05-06 | — | — | EP | disclosed |
| WO-2014002051-A2 | COMPLEMENT PATHWAY MODULATORS AND USES THEREOF | NOVARTIS AG (CH) | 2014-01-03 | — | — | WO | disclosed |