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Sugi Predict / Compounds / SCHEMBL15540537

SCHEMBL15540537

SCHEMBL15540537

CCOc1cc(=O)n(C)cc1-c1cc(NS(=O)(=O)CC)ccc1OCC1CC1

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 20/20 0.69
▸ BRDT Q58F21 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15540489 0.90 BRD4 (0.67) BRD4BRDT
SCHEMBL15539767 0.86 BRD4 (0.81) BRD4BRDT
SCHEMBL15541275 0.85 BRD4 (0.82) BRD4
SCHEMBL16715353 0.82 BRD4 (0.75) BRD4BRDT
SCHEMBL15541387 0.82 BRD4 (1.00) BRD4
SCHEMBL15552405 0.81 BRD4 (0.51) BRD4
SCHEMBL15551106 0.81 BRD4 (0.72) BRD4BRDT
SCHEMBL20155131 0.81 BRD4 (0.68) BRD4BRDT
SCHEMBL15541486 0.81 BRD4 (0.75) BRD4BRDT
SCHEMBL15540694 0.80 BRD4 (0.73) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2858990-B1 PYRIDINONE AND PYRIDAZINONE DERIVATIVES ABBVIE INC (US) 2018-05-16 — — EP claimed
EP-2858990-A1 PYRIDINONE AND PYRIDAZINONE DERIVATIVES AbbVie Inc. (US) 2015-04-15 — — EP claimed
WO-2013188381-A1 PYRIDINONE AND PYRIDAZINONE DERIVATIVES ABBVIE INC. (US) 2013-12-19 — — WO claimed
EP-2858990-B1 PYRIDINONE AND PYRIDAZINONE DERIVATIVES ABBVIE INC (US) 2018-05-16 — — EP disclosed
EP-2858990-A1 PYRIDINONE AND PYRIDAZINONE DERIVATIVES AbbVie Inc. (US) 2015-04-15 — — EP disclosed
WO-2013188381-A1 PYRIDINONE AND PYRIDAZINONE DERIVATIVES ABBVIE INC. (US) 2013-12-19 — — WO disclosed