Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 20/20 | 1.00 |
| ▸ | PIM3 | Q86V86 | 18/20 | 1.00 |
| ▸ | PIM2 | Q9P1W9 | 18/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15401492 | 1.00 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL15400461 | 0.84 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL15544275 | 0.84 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL15400154 | 0.83 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL15543927 | 0.83 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL15400744 | 0.81 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL15400384 | 0.81 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL15544510 | 0.80 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL15401232 | 0.80 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL15401800 | 0.80 | PIM1 (1.00) | PIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867232-A1 | 5-AZAINDAZOLE COMPOUNDS AND METHODS OF USE | F. Hoffmann-La Roche AG (CH) | 2015-05-06 | — | — | EP | disclosed |
| WO-2014001377-A1 | 5-AZAINDAZOLE COMPOUNDS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2014-01-03 | — | — | WO | disclosed |