Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCH | P24723 | 13/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 13/20 | 0.55 |
| ▸ | PRKCE | Q02156 | 12/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 11/20 | 0.55 |
| ▸ | PRKCA | P17252 | 9/20 | 0.55 |
| ▸ | PRKCB | P05771 | 6/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.55 |
| ▸ | PKN1 | Q16512 | 2/20 | 0.55 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.46 |
| ▸ | LATS1 | O95835 | 6/20 | 0.45 |
| ▸ | LATS2 | Q9NRM7 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3331375 | 0.88 | PRKCD (0.60) | PRKCHPRKCDPRKCEPRKCQPRKCA | |
| SCHEMBL1424194 | 0.87 | PRKCD (0.49) | PRKCHPRKCDPRKCEPRKCQPRKCA | |
| SCHEMBL3322963 | 0.85 | DYRK1A (0.46) | PRKCHPRKCDPRKCEPRKCQPRKCA | |
| SCHEMBL1424201 | 0.83 | PRKCH (0.66) | PRKCHPRKCDPRKCEPRKCQPRKCA | |
| SCHEMBL29634278 | 0.81 | PRKCD (0.57) | PRKCHPRKCDPRKCEPRKCQPRKCA | |
| SCHEMBL3325764 | 0.81 | PRKCD (0.57) | PRKCHPRKCDPRKCEPRKCQPRKCA | |
| Ammonia Solution, Strong SCHEMBL19611956 | 0.80 | PRKCD (0.56) | PRKCHPRKCDPRKCEPRKCQPRKCA | |
| SCHEMBL3327832 | 0.78 | PRKCD (0.55) | PRKCHPRKCDPRKCEPRKCQPRKCA | |
| SCHEMBL3322844 | 0.78 | PRKCD (0.54) | PRKCHPRKCDPRKCEPRKCQPRKCA | |
| SCHEMBL3325907 | 0.77 | PRKCH (0.60) | PRKCHPRKCDPRKCEPRKCQPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2846784-A1 | COMPOUNDS USEFUL FOR PROMOTING PROTEIN DEGRADATION AND METHODS USING SAME | Yale University (US) | 2015-03-18 | — | — | EP | disclosed |
| WO-2013170147-A1 | COMPOUNDS USEFUL FOR PROMOTING PROTEIN DEGRADATION AND METHODS USING SAME | YALE UNIVERSITY (US) | 2013-11-14 | — | — | WO | disclosed |