Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.83 |
| ▸ | CA2 | P00918 | 1/20 | 0.83 |
| ▸ | CA9 | Q16790 | 1/20 | 0.83 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL4330853 | 1.00 | — | — | |
| Bicarbonate SCHEMBL25390 | 1.00 | — | — | |
| Bicarbonate SCHEMBL5173835 | 1.00 | — | — | |
| Bicarbonate SCHEMBL10353161 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL17309693 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL8835794 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL5173817 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL5304565 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL11678451 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL25426249 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855357-B1 | PRODUCTION OF HIGH PURITY LITHIUM FLUORIDE | LANXESS DEUTSCHLAND GMBH (DE) | 2019-11-13 | — | — | EP | disclosed |
| EP-2984038-A2 | LOW-CHLORIDE ELECTROLYTE | Lanxess Deutschland GmbH (DE) | 2016-02-17 | — | — | EP | disclosed |
| EP-2900593-A1 | PRODUCTION OF HIGH-PURITY LITHIUM DIFLUOROPHOSPHATE | LANXESS Deutschland GmbH (DE) | 2015-08-05 | — | — | EP | disclosed |
| EP-2855356-A1 | HIGH-PURITY LITHIUM HEXAFLUOROPHOSPHATE | LANXESS Deutschland GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |
| EP-2855357-A1 | PRODUCTION OF HIGH-PURITY LITHIUM FLUORIDE | LANXESS Deutschland GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |
| WO-2014167055-A2 | LOW-CHLORIDE ELECTROLYTE | LANXESS DEUTSCHLAND GMBH (DE) | 2014-10-16 | — | — | WO | disclosed |
| EP-2789583-A1 | Low chloride electrolyte | LANXESS Deutschland GmbH (DE) | 2014-10-15 | — | — | EP | disclosed |
| WO-2013174938-A1 | PRODUCTION OF HIGH-PURITY LITHIUM FLUORIDE | LANXESS DEUTSCHLAND GMBH (DE) | 2013-11-28 | — | — | WO | disclosed |
| WO-2013174941-A1 | HIGH-PURITY LITHIUM HEXAFLUOROPHOSPHATE | LANXESS DEUTSCHLAND GMBH (DE) | 2013-11-28 | — | — | WO | disclosed |