Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 20/20 | 0.44 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 7/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL391025 | 0.80 | MAP2K1 (0.47) | MAP2K1MAP2K2CA2 | |
| SCHEMBL391574 | 0.78 | MAP2K1 (0.53) | MAP2K1MAP2K2CA2 | |
| SCHEMBL387833 | 0.73 | MAP2K1 (0.51) | MAP2K1MAP2K2CA2 | |
| SCHEMBL392673 | 0.73 | MAP2K1 (0.50) | MAP2K1MAP2K2CA2 | |
| SCHEMBL10251094 | 0.71 | MAP2K1 (0.48) | MAP2K1MAP2K2CA2 | |
| SCHEMBL1516527 | 0.71 | MAP2K1 (0.45) | MAP2K1MAP2K2 | |
| SCHEMBL486695 | 0.70 | MAP2K1 (0.57) | MAP2K1MAP2K2 | |
| SCHEMBL685422 | 0.70 | MAP2K1 (0.61) | MAP2K1MAP2K2CA2 | |
| SCHEMBL720442 | 0.70 | MAP2K1 (0.51) | MAP2K1MAP2K2 | |
| SCHEMBL2295064 | 0.70 | MAP2K1 (0.57) | MAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491015-A1 | SUBSTITUTED BENZOSULPHONAMIDES | Bayer Pharma Aktiengesellschaft (DE) | 2012-08-29 | — | — | EP | disclosed |
| WO-2011047788-A1 | SUBSTITUTED BENZOSULPHONAMIDES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-04-28 | — | — | WO | disclosed |