Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 19/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15534443 | 0.89 | TNIK (0.75) | TNIK | |
| SCHEMBL16699546 | 0.81 | TNIK (0.75) | TNIK | |
| SCHEMBL16699517 | 0.77 | TNIK (0.77) | TNIK | |
| SCHEMBL16699031 | 0.76 | TNIK (0.62) | TNIK | |
| SCHEMBL2367226 | 0.76 | TNIK (0.61) | TNIKNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL16710220 | 0.75 | TNIK (1.00) | TNIK | |
| SCHEMBL16698958 | 0.75 | TNIK (0.71) | TNIK | |
| SCHEMBL16699999 | 0.74 | TNIK (1.00) | TNIK | |
| SCHEMBL16701278 | 0.73 | TNIK (0.79) | TNIK | |
| SCHEMBL16699946 | 0.73 | TNIK (0.72) | TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855470-A1 | NOVEL BICYCLIC THIAZOLE COMPOUNDS | Carna Biosciences Inc. (JP) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013176293-A1 | NOVEL BICYCLIC THIAZOLE COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2013-11-28 | — | — | WO | disclosed |