Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BCL9 | O00512 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15548696 | 0.98 | KMT2A (0.50) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL15548945 | 0.95 | KMT2A (0.53) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL2291105 | 0.85 | PRSS1 (0.54) | KMT2ASMN1; SMN2RECQLELANEMAPT | |
| SCHEMBL15547473 | 0.84 | MEN1 (0.49) | KMT2AESR1HIF1ARECQLELANE | |
| SCHEMBL17974115 | 0.84 | PRSS1 (0.56) | KMT2ASMN1; SMN2RECQLELANEMAPT | |
| SCHEMBL15547527 | 0.83 | MEN1 (0.48) | KMT2AESR1HIF1ARECQLELANE | |
| SCHEMBL15548694 | 0.83 | MEN1 (0.48) | KMT2AESR1HIF1ARECQLELANE | |
| SCHEMBL15548658 | 0.83 | MEN1 (0.48) | KMT2AESR1HIF1ARECQLELANE | |
| SCHEMBL15548025 | 0.83 | MEN1 (0.48) | KMT2AESR1HIF1ARECQLELANE | |
| SCHEMBL12004884 | 0.83 | PRSS1 (0.55) | KMT2ASMN1; SMN2ESR1RECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872538-A1 | ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME | Indian Oil Corporation Ltd (IN) | 2015-05-20 | — | — | EP | claimed |
| WO-2014013401-A1 | ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME | INDIAN OIL CORPORATION LIMITED (IN) | 2014-01-23 | — | — | WO | claimed |