Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14740315 | 1.00 | CNR1 (0.70) | CNR1ALDH1A1FAAHCNR2TRPM8 | |
| SCHEMBL14740218 | 1.00 | CNR1 (0.70) | CNR1ALDH1A1FAAHCNR2TRPM8 | |
| SCHEMBL14739465 | 1.00 | CNR1 (0.70) | CNR1ALDH1A1FAAHCNR2TRPM8 | |
| SCHEMBL14739842 | 1.00 | CNR1 (0.70) | CNR1ALDH1A1FAAHCNR2TRPM8 | |
| SCHEMBL14739797 | 1.00 | CNR1 (0.70) | CNR1ALDH1A1FAAHCNR2TRPM8 | |
| SCHEMBL14739462 | 1.00 | CNR1 (0.70) | CNR1ALDH1A1FAAHCNR2TRPM8 | |
| SCHEMBL14739844 | 1.00 | CNR1 (0.70) | CNR1ALDH1A1FAAHCNR2TRPM8 | |
| SCHEMBL14740217 | 1.00 | CNR1 (0.70) | CNR1ALDH1A1FAAHCNR2TRPM8 | |
| SCHEMBL14739796 | 1.00 | CNR1 (0.70) | CNR1ALDH1A1FAAHCNR2TRPM8 | |
| SCHEMBL14740313 | 1.00 | CNR1 (0.70) | CNR1ALDH1A1FAAHCNR2TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2854787-A2 | METHODS OF LOWERING PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) | Catabasis Pharmaceuticals, Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013177536-A2 | METHODS OF LOWERING PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) | CATABASIS PHARMACEUTICALS, INC. (US) | 2013-11-28 | — | — | WO | disclosed |