Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | FABP4 | P15090 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852578 | 0.96 | MEN1 (0.60) | MEN1KMT2ANPY5RALDH1A1CA1 | |
| SCHEMBL32689397 | 0.95 | NPY5R (0.61) | MEN1KMT2ANPY5RALDH1A1CA1 | |
| SCHEMBL5658106 | 0.95 | NPY5R (0.61) | MEN1KMT2ANPY5RALDH1A1CA1 | |
| SCHEMBL4178616 | 0.92 | KMT2A (0.64) | MEN1KMT2ANPY5RALDH1A1CA1 | |
| SCHEMBL31284709 | 0.87 | KMT2A (0.68) | MEN1KMT2ANPY5RALDH1A1CA1 | |
| SCHEMBL29571128 | 0.87 | KMT2A (0.68) | MEN1KMT2ANPY5RALDH1A1CA1 | |
| SCHEMBL27006685 | 0.87 | KMT2A (0.68) | MEN1KMT2ANPY5RALDH1A1CA1 | |
| SCHEMBL13091921 | 0.86 | NPY5R (0.54) | MEN1KMT2ANPY5RALDH1A1CA1 | |
| SCHEMBL3540913 | 0.86 | KMT2A (0.66) | MEN1KMT2ANPY5RALDH1A1CA1 | |
| SCHEMBL7006320 | 0.85 | NPY5R (0.62) | MEN1KMT2ANPY5RALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014018913-A2 | SANTACRUZAMATE A COMPOSITIONS AND ANALOGS AND METHODS OF USE | UNIVERSITY OF CONNECTICUT (US) | 2014-01-30 | — | — | WO | disclosed |