Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | DGKA | P23743 | 1/20 | 0.53 |
| ▸ | BCL9 | O00512 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.50 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696854 | 1.00 | KMT2A (0.68) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL38661498 | 1.00 | KMT2A (0.68) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL5696798 | 1.00 | KMT2A (0.68) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL5696715 | 1.00 | KMT2A (0.68) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL15549194 | 0.98 | KMT2A (0.66) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL10407329 | 0.98 | KMT2A (0.65) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL18087016 | 0.94 | KMT2A (0.62) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL15548919 | 0.94 | KMT2A (0.62) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL1275970 | 0.93 | KMT2A (0.61) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL3397296 | 0.93 | KMT2A (0.61) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872538-A1 | ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME | Indian Oil Corporation Ltd (IN) | 2015-05-20 | — | — | EP | claimed |
| WO-2014013401-A1 | ZIEGLER-NATTA CATALYST SYSTEMS COMPRISING A 1,2-PHENYLENEDIOATE AS INTERNAL DONOR AND PROCESS FOR PREPARING THE SAME | INDIAN OIL CORPORATION LIMITED (IN) | 2014-01-23 | — | — | WO | claimed |