Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 20/20 | 0.56 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30947514 | 1.00 | PDE9A (0.56) | PDE9APDE1CACHE | |
| SCHEMBL15551426 | 0.90 | PDE9A (0.60) | PDE9APDE1CACHE | |
| SCHEMBL15552324 | 0.88 | PDE9A (0.71) | PDE9APDE1CACHE | |
| SCHEMBL15552268 | 0.86 | PDE9A (0.70) | PDE9APDE1CACHE | |
| SCHEMBL15550624 | 0.86 | PDE9A (0.61) | PDE9APDE1CACHE | |
| SCHEMBL30947484 | 0.86 | PDE9A (0.61) | PDE9APDE1CACHE | |
| SCHEMBL15550257 | 0.84 | PDE9A (0.62) | PDE9APDE1CACHE | |
| SCHEMBL15551033 | 0.83 | PDE9A (0.61) | PDE9APDE1CACHE | |
| SCHEMBL15550706 | 0.79 | PDE9A (0.73) | PDE9APDE1C | |
| SCHEMBL15551640 | 0.77 | PDE9A (0.64) | PDE9APDE1CACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014016789-A1 | PYRAZOLO[3,4-D]PYRIMIDIN-4(5H)-ONE DERIVATIVES AS PDE9 INHIBITORS | CELON PHARMA S.A. (PL) | 2014-01-30 | — | — | WO | claimed |
| WO-2024107445-A1 | ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES | FREEDOM BIOSCIENCES, INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2014016789-A1 | PYRAZOLO[3,4-D]PYRIMIDIN-4(5H)-ONE DERIVATIVES AS PDE9 INHIBITORS | CELON PHARMA S.A. (PL) | 2014-01-30 | — | — | WO | disclosed |