Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 18/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15550143 | 0.90 | CYP26A1 (0.57) | CYP26A1ADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL15550398 | 0.90 | CYP26A1 (0.57) | CYP26A1ADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL15551192 | 0.89 | CYP26A1 (0.51) | CYP26A1ADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL15550067 | 0.87 | CYP26A1 (0.59) | CYP26A1ADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL15548785 | 0.86 | CYP26A1 (0.60) | CYP26A1ADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL15551301 | 0.83 | CYP26A1 (0.62) | CYP26A1ADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL15551242 | 0.81 | CYP26A1 (0.58) | CYP26A1ADRA2AADRA2BADRA2CCYP3A4 | |
| SCHEMBL4283358 | 0.72 | CYP26A1 (1.00) | CYP26A1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4284727 | 0.69 | CYP26A1 (0.64) | CYP26A1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4284732 | 0.68 | CYP26A1 (0.64) | CYP26A1CYP3A4CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014093960-A1 | COMPOSITIONS AND METHODS FOR TREATING DISEASE | ANGION BIOMEDICA CORP. (US) | 2014-06-19 | — | — | WO | claimed |
| WO-2014015137-A2 | COMPOSITIONS AND METHODS FOR TREATING DYSPROLIFERATIVE DISEASES | ANGION BIOMEDICA CORP. (US) | 2014-01-23 | — | — | WO | claimed |
| WO-2014093960-A1 | COMPOSITIONS AND METHODS FOR TREATING DISEASE | ANGION BIOMEDICA CORP. (US) | 2014-06-19 | — | — | WO | disclosed |