Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 18/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15550585 | 0.90 | BRD4 (0.51) | BRD4 | |
| SCHEMBL15551236 | 0.87 | BRD4 (0.57) | BRD4 | |
| SCHEMBL15550954 | 0.87 | BRD4 (0.71) | BRD4 | |
| SCHEMBL15554205 | 0.86 | BRD4 (0.54) | BRD4 | |
| SCHEMBL15551540 | 0.86 | BRD4 (0.51) | BRD4 | |
| SCHEMBL15549928 | 0.84 | BRD4 (0.53) | BRD4 | |
| SCHEMBL15551876 | 0.83 | BRD4 (0.50) | BRD4 | |
| SCHEMBL15552317 | 0.82 | BRD4 (0.54) | BRD4 | |
| SCHEMBL15551269 | 0.81 | BRD4 (0.53) | BRD4 | |
| SCHEMBL15551393 | 0.80 | BRD4 (0.54) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884451-A | Pyridinone and pyridazinone derivatives | ABBVIE INC | 2015-09-02 | — | — | CN | disclosed |
| EP-2858990-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | AbbVie Inc. (US) | 2015-04-15 | — | — | EP | disclosed |
| EP-2858982-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | AbbVie Inc. (US) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013185284-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | ABBOTT LABORATORIES (US) | 2013-12-19 | — | — | WO | disclosed |
| WO-2013188381-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | ABBVIE INC. (US) | 2013-12-19 | — | — | WO | disclosed |