Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.63 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15555286 | 1.00 | EPHX1 (0.63) | EPHX1BACE1BACE2POLBHDAC3 | |
| SCHEMBL15553655 | 1.00 | EPHX1 (0.63) | EPHX1BACE1BACE2POLBHDAC3 | |
| Hydrochloric Acid SCHEMBL15553133 | 0.98 | EPHX1 (0.61) | EPHX1BACE1BACE2POLBHDAC3 | |
| Hydrochloric Acid SCHEMBL15553761 | 0.98 | EPHX1 (0.61) | EPHX1BACE1BACE2POLBHDAC3 | |
| Hydrochloric Acid SCHEMBL15554159 | 0.98 | EPHX1 (0.61) | EPHX1BACE1BACE2POLBHDAC3 | |
| SCHEMBL15553838 | 0.90 | EPHX1 (0.51) | EPHX1BACE1BACE2POLBHDAC3 | |
| SCHEMBL15554428 | 0.90 | EPHX1 (0.51) | EPHX1BACE1BACE2POLBHDAC3 | |
| SCHEMBL15553478 | 0.90 | EPHX1 (0.51) | EPHX1BACE1BACE2POLBALDH1A1 | |
| SCHEMBL15553362 | 0.90 | EPHX1 (0.51) | EPHX1BACE1BACE2HDAC3HDAC1 | |
| SCHEMBL15553274 | 0.90 | EPHX1 (0.51) | EPHX1BACE1BACE2POLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014016766-A1 | GUANIDINE DERIVATIVES AS TRPC MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2014-01-30 | — | — | WO | claimed |
| WO-2014016766-A1 | GUANIDINE DERIVATIVES AS TRPC MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2014-01-30 | — | — | WO | disclosed |