Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.34 |
| ▸ | MICA | Q29983 | 2/20 | 0.34 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7232612 | 0.83 | MAPT (0.56) | MAPTNPC1POLBRBP4ALDH1A1 | |
| SCHEMBL4431071 | 0.82 | NPC1 (0.49) | MAPTNPC1POLBRBP4ALDH1A1 | |
| SCHEMBL15043768 | 0.81 | MAPT (0.57) | MAPTNPC1POLBRBP4ALDH1A1 | |
| SCHEMBL25214530 | 0.79 | MAPT (0.55) | MAPTNPC1POLBRBP4ALDH1A1 | |
| SCHEMBL22048230 | 0.79 | MAPT (0.47) | MAPTNPC1POLBRBP4ALDH1A1 | |
| SCHEMBL13797528 | 0.78 | NPC1 (0.49) | MAPTNPC1POLBRBP4ALDH1A1 | |
| SCHEMBL9018164 | 0.78 | MAPT (0.54) | MAPTNPC1POLBRBP4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27573348 | 0.77 | NPC1 (0.51) | MAPTNPC1POLBRBP4ALDH1A1 | |
| SCHEMBL15594536 | 0.77 | MAPT (0.51) | MAPTNPC1POLBRBP4ALDH1A1 | |
| SCHEMBL7230316 | 0.77 | MAPT (0.59) | MAPTNPC1POLBRBP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014023531-A1 | TRIFLUOROMETHYLPYRIDINE CARBOXAMIDES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-13 | — | — | WO | disclosed |
| WO-2014023531-A1 | TRIFLUOROMETHYLPYRIDINE CARBOXAMIDES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-13 | — | — | WO | disclosed |