Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 20/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17007707 | 1.00 | GPR6 (0.86) | GPR6 | |
| SCHEMBL17007706 | 1.00 | GPR6 (0.86) | GPR6 | |
| SCHEMBL17007718 | 0.93 | GPR6 (1.00) | GPR6 | |
| SCHEMBL17007638 | 0.91 | GPR6 (0.85) | GPR6 | |
| SCHEMBL17007674 | 0.91 | GPR6 (0.85) | GPR6 | |
| SCHEMBL17007637 | 0.91 | GPR6 (0.85) | GPR6 | |
| SCHEMBL15567253 | 0.90 | GPR6 (0.73) | GPR6 | |
| SCHEMBL15567235 | 0.89 | GPR6 (0.73) | GPR6 | |
| SCHEMBL15567234 | 0.89 | GPR6 (0.73) | GPR6 | |
| SCHEMBL15566665 | 0.88 | GPR6 (0.86) | GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882722-A1 | QUINOXALINE DERIVATIVES AS GPR6 MODULATORS | Envoy Therapeutics Inc. (US) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014028479-A1 | QUINOXALINE DERIVATIVES AS GPR6 MODULATORS | ENVOY THERAPEUTICS, INC. (US) | 2014-02-20 | — | — | WO | disclosed |