Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14643094 | 0.90 | PTK2 (0.84) | PTK2 | |
| SCHEMBL14576350 | 0.88 | PTK2 (1.00) | PTK2 | |
| SCHEMBL12478987 | 0.87 | PTK2 (0.83) | PTK2 | |
| SCHEMBL14577085 | 0.86 | PTK2 (1.00) | PTK2 | |
| SCHEMBL12479002 | 0.85 | PTK2 (1.00) | PTK2 | |
| SCHEMBL12478738 | 0.85 | PTK2 (0.86) | PTK2 | |
| SCHEMBL12479296 | 0.85 | PTK2 (1.00) | PTK2 | |
| SCHEMBL14643156 | 0.84 | PTK2 (0.76) | PTK2 | |
| SCHEMBL14577232 | 0.84 | PTK2 (1.00) | PTK2 | |
| SCHEMBL14643093 | 0.82 | PTK2 (0.82) | PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9421205-B2 | FAK inhibitors | Cancer Therapeutics CRC Pty Ltd. (AU) | 2016-08-23 | — | — | US | disclosed |
| WO-2014027199-A1 | FAK AND FLT3 INHIBITORS | CANCER THERAPEUTICS CRC PTY LTD (AU) | 2014-02-20 | — | — | WO | disclosed |