⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27738066 | 1.00 | — | — | |
| SCHEMBL27557014 | 1.00 | — | — | |
| Methane SCHEMBL23088734 | 0.00 | — | — | |
| Hydrogen Sulfide SCHEMBL23805181 | 0.00 | — | — | |
| SCHEMBL23528133 | 0.00 | — | — | |
| SCHEMBL23462252 | 0.00 | — | — | |
| SCHEMBL25435013 | 0.00 | — | — | |
| SCHEMBL23462141 | 0.00 | — | — | |
| Potassium Ion SCHEMBL23462035 | 0.00 | CA4 (0.50) | — | |
| SCHEMBL23358113 | 0.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308853-A1 | Process for the preparation of aminopyrimidines | AstraZeneca AB (SE) | 2011-04-13 | — | — | EP | claimed |
| US-20100324289-A1 | Chemical Process | ASTRAZENECA AB (SE) | 2010-12-23 | — | — | US | claimed |
| US-20070219371-A1 | Chemical Process | ASTRAZENECA AB (SE) | 2007-09-20 | — | — | US | claimed |
| EP-2308853-A1 | Process for the preparation of aminopyrimidines | AstraZeneca AB (SE) | 2011-04-13 | — | — | EP | disclosed |
| US-20100324289-A1 | Chemical Process | ASTRAZENECA AB (SE) | 2010-12-23 | — | — | US | disclosed |
| CN-101851212-A | Chemical process | ASTRAZENECA AB | 2010-10-06 | — | — | CN | disclosed |
| US-7799914-B2 | Chemical process | ASTRAZENECA AB (SE) | 2010-09-21 | — | — | US | disclosed |
| CN-1938284-B | Chemical process | ASTRAZENECA AB | 2010-08-11 | — | — | CN | disclosed |
| US-20070219371-A1 | Chemical Process | ASTRAZENECA AB (SE) | 2007-09-20 | — | — | US | disclosed |
| CN-1938284-A | Chemical process | ASTRAZENECA AB (SE) | 2007-03-28 | — | — | CN | disclosed |
| EP-1751117-A2 | PROCESS FOR THE PREPARATION OF AMINOPYRIMIDINES | AstraZeneca AB (SE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005095358-A2 | PROCESS FOR THE PREPARATION OF AMINOPYRIMIDINES | ASTRAZENECA AB (SE) | 2005-10-13 | — | — | WO | disclosed |