Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 20/20 | 0.76 |
| ▸ | KDR | P35968 | 6/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15568714 | 0.92 | FLT4 (0.76) | FLT4KDR | |
| SCHEMBL15506905 | 0.87 | FLT4 (1.00) | FLT4KDR | |
| SCHEMBL15513707 | 0.85 | FLT4 (0.82) | FLT4KDR | |
| SCHEMBL15506854 | 0.85 | FLT4 (1.00) | FLT4KDR | |
| SCHEMBL15506897 | 0.83 | FLT4 (1.00) | FLT4KDR | |
| SCHEMBL15506904 | 0.80 | FLT4 (1.00) | FLT4KDR | |
| SCHEMBL15506611 | 0.79 | FLT4 (1.00) | FLT4KDR | |
| SCHEMBL15506906 | 0.79 | FLT4 (1.00) | FLT4KDR | |
| SCHEMBL15506640 | 0.79 | FLT4 (1.00) | FLT4KDR | |
| SCHEMBL15506850 | 0.78 | FLT4 (1.00) | FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2885291-A1 | VEGFR3 INHIBITORS | Cancer Therapeutics Crc Pty Limited (AU) | 2015-06-24 | — | — | EP | disclosed |
| WO-2014026243-A1 | VEGFR3 INHIBITORS | CANCER THERAPEUTICS CRC PTY LIMITED (AU) | 2014-02-20 | — | — | WO | disclosed |