SCHEMBL15570802

SCHEMBL15570802

CC(C)NCCC(CNC(=O)O)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15597291 0.85 MEN1 (0.40)
SCHEMBL19330417 0.83 CYP2D6 (0.42) CYP2D6CYP2C19
SCHEMBL30554097 0.79 CYP2D6 (0.38) CYP2D6CYP2C19
SCHEMBL18990458 0.79 CYP2D6 (0.38) CYP2D6CYP2C19
SCHEMBL18340836 0.79 CYP2D6 (0.38) CYP2D6CYP2C19
SCHEMBL19330547 0.78 CYP2D6 (0.37) CYP2D6CYP2C19
SCHEMBL19330741 0.78 CYP2D6 (0.37) CYP2D6CYP2C19
SCHEMBL18341021 0.78 CYP2D6 (0.37) CYP2D6CYP2C19
SCHEMBL18990212 0.78 CYP2D6 (0.37) CYP2D6CYP2C19
SCHEMBL18990213 0.78 CYP2D6 (0.37) CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014031872-A2 SMALL MOLECULE INHIBITORS FOR TREATING PARASITIC INFECTIONS THE BROAD INSTITUTE, INC. (US) 2014-02-27 WO disclosed