Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 9/20 | 0.91 |
| ▸ | CA1 | P00915 | 9/20 | 0.91 |
| ▸ | CA2 | P00918 | 9/20 | 0.91 |
| ▸ | CA9 | Q16790 | 9/20 | 0.91 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL476380 | 0.95 | CA12 (1.00) | CA12CA1CA2CA9NAAA | |
| Potassium Ion SCHEMBL8509938 | 0.95 | CA12 (1.00) | CA12CA1CA2CA9NAAA | |
| SCHEMBL9719002 | 0.95 | CA12 (0.91) | CA12CA1CA2CA9NAAA | |
| SCHEMBL11608338 | 0.95 | CA12 (0.91) | CA12CA1CA2CA9NAAA | |
| Zinc Ion SCHEMBL15157720 | 0.95 | CA12 (0.91) | CA12CA1CA2CA9NAAA | |
| Potassium Ion SCHEMBL2503956 | 0.95 | CA12 (1.00) | CA12CA1CA2CA9NAAA | |
| SCHEMBL10976175 | 0.95 | CA12 (0.91) | CA12CA1CA2CA9NAAA | |
| SCHEMBL15158111 | 0.95 | CA12 (0.91) | CA12CA1CA2CA9NAAA | |
| SCHEMBL9304545 | 0.95 | CA12 (0.91) | CA12CA1CA2CA9NAAA | |
| Zinc Ion SCHEMBL16414386 | 0.95 | CA12 (0.91) | CA12CA1CA2CA9NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841482-B1 | POLYURETHANES MADE USING BISMUTH THIOCARBAMATE OR THIOCARBONATE SALTS AS CATALYSTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-02-12 | — | — | EP | disclosed |
| US-9416214-B2 | Polyurethanes made using bismuth thiocarbamate or thiocarbonate salts as catalysts | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-08-16 | — | — | US | disclosed |
| US-20150065675-A1 | POLYURETHANES MADE USING BISMUTH THIOCARBAMATE OR THIOCARBONATE SALTS AS CATALYSTS | DOW GLOBAL TECHNOLOGIES LLC. | 2015-03-05 | — | — | US | disclosed |
| EP-2841482-A1 | POLYURETHANES MADE USING BISMUTH THIOCARBAMATE OR THIOCARBONATE SALTS AS CATALYSTS | Dow Global Technologies LLC (US) | 2015-03-04 | — | — | EP | disclosed |
| WO-2014031181-A1 | POLYURETHANES MADE USING BISMUTH THIOCARBAMATE OR THIOCARBONATE SALTS AS CATALYSTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-02-27 | — | — | WO | disclosed |