⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941675 | 0.97 | — | — | |
| SCHEMBL11255913 | 0.90 | — | — | |
| SCHEMBL11658732 | 0.88 | PTPN7 (0.48) | — | |
| SCHEMBL8551377 | 0.88 | PTPN7 (0.48) | — | |
| SCHEMBL8030954 | 0.88 | PTPN7 (0.48) | — | |
| SCHEMBL7572259 | 0.88 | — | — | |
| SCHEMBL9732267 | 0.88 | PTPN7 (0.48) | — | |
| SCHEMBL55033 | 0.82 | TSHR (0.53) | — | |
| SCHEMBL11854278 | 0.79 | TSHR (0.50) | — | |
| SCHEMBL796575 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673446-A1 | FLOW CHEMISTRY PROCESS FOR PREPARING AZA-BICYCLIC HETEROARYL COMPOUNDS | Actinogen Medical Limited (AU) | 2026-01-07 | — | — | EP | claimed |
| WO-2024178474-A1 | FLOW CHEMISTRY PROCESS FOR PREPARING AZA-BICYCLIC HETEROARYL COMPOUNDS | Actinogen Medical Limited (AU) | 2024-09-06 | — | — | WO | claimed |
| US-10329441-B2 | Aqueous pigment dispersion, pigment dispersant, and core-shell polymer particles | DIC CORPORATION (JP) | 2019-06-25 | — | — | US | claimed |
| US-20130131356-A1 | PREPARATION OF PROTECTED ALPHA-KETO BETA-AMINO ESTERS AND AMIDES | VERTEX PHAMACEUTICALS INCORPORATED (US) | 2013-05-23 | — | — | US | claimed |
| JP-2011526895-A | — | — | 2011-10-20 | — | — | JP | claimed |
| US-20110213161-A1 | Preparation of Protected Alpha-Keto Beta-Amino Esters and Amides | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-09-01 | — | — | US | claimed |
| EP-2303858-A1 | PREPARATION OF PROTECTED ALPHA-KETO BETA-AMINO ESTERS AND AMIDES | Vertex Pharmceuticals Incorporated (US) | 2011-04-06 | — | — | EP | claimed |
| WO-2010002474-A1 | PREPARATION OF PROTECTED ALPHA-KETO BETA-AMINO ESTERS AND AMIDES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-01-07 | — | — | WO | claimed |
| EP-4737441-A1 | METHOD FOR PRODUCING ELECTROPHILIC SUBSTITUTED AROMATIC COMPOUND | FUJIFILM Corporation (JP) | 2026-05-06 | — | — | EP | disclosed |
| US-20260070931-A1 | METHOD FOR MANUFACTURING ELECTROPHILIC SUBSTITUTED AROMATIC COMPOUND | FUJIFILM CORPORATION (JP) | 2026-03-12 | — | — | US | disclosed |
| EP-4673446-A1 | FLOW CHEMISTRY PROCESS FOR PREPARING AZA-BICYCLIC HETEROARYL COMPOUNDS | Actinogen Medical Limited (AU) | 2026-01-07 | — | — | EP | disclosed |
| US-12460039-B2 | Block copolymer intermediate, block copolymer, and methods for producing same | DIC CORPORATION (JP) | 2025-11-04 | — | — | US | disclosed |
| WO-2025199647-A1 | C4'-MODIFIED NUCLEOSIDE ANALOGUES AND SYNTHETIC METHODS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2025-10-02 | — | — | WO | disclosed |
| US-12331148-B2 | Block copolymer intermediate, block copolymer, and production methods for same | DIC CORPORATION (JP) | 2025-06-17 | — | — | US | disclosed |
| US-4540826-A | A,W-DIHALIDE, METAL ACETYLIDE, HYDROGENATION, OXIDATION | PHILLIPS PETROLEUM COMPANY (US) | 1985-09-10 | — | — | US | disclosed |
| US-4315032-A | ANTITHROMBOGENIC AGENTS, ANTIULCER AGENTS | TEITIN LIMITED (JP) | 1982-02-09 | — | — | US | disclosed |
| EP-0019475-A2 | Process for preparing adjacently disubstituted ketones, novel prostaglandins E1 and anti-thrombotic compositions containing them | TEIJIN LIMITED (JP) | 1980-11-26 | — | — | EP | disclosed |
| US-4175201-A | Chemical synthesis | UNIVERSITY OF CHICAGO (US) | 1979-11-20 | — | — | US | disclosed |
| US-4139717-A | 1,3-Dicarbonyl compounds | TEIJIN LIMITED (JP) | 1979-02-13 | — | — | US | disclosed |
| US-4018820-A | Chemical synthesis | THE UNIVERSITY OF CHICAGO (US) | 1977-04-19 | — | — | US | disclosed |