Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 20/20 | 0.82 |
| ▸ | HDAC1 | Q13547 | 20/20 | 0.82 |
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.82 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15580235 | 0.90 | HDAC3 (1.00) | HDAC3HDAC1HDAC6HDAC4 | |
| SCHEMBL15580292 | 0.89 | HDAC6 (1.00) | HDAC3HDAC1HDAC6HDAC4 | |
| SCHEMBL15580206 | 0.86 | HDAC3 (1.00) | HDAC3HDAC1HDAC6HDAC4 | |
| SCHEMBL15580217 | 0.86 | HDAC3 (1.00) | HDAC3HDAC1HDAC6HDAC4 | |
| SCHEMBL19114268 | 0.86 | HDAC6 (0.67) | HDAC3HDAC1HDAC6HDAC4 | |
| SCHEMBL15580219 | 0.83 | HDAC6 (1.00) | HDAC3HDAC1HDAC6HDAC4 | |
| SCHEMBL15580238 | 0.83 | HDAC6 (1.00) | HDAC3HDAC1HDAC6HDAC4 | |
| SCHEMBL15580239 | 0.81 | HDAC6 (1.00) | HDAC3HDAC1HDAC6HDAC4 | |
| SCHEMBL15580207 | 0.81 | HDAC6 (1.00) | HDAC3HDAC1HDAC6HDAC4 | |
| SCHEMBL15580233 | 0.79 | HDAC1 (1.00) | HDAC3HDAC1HDAC6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2708534-B1 | THIAZOLE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SHANGHAI THEORION PHARMACEUTICAL CO LTD (CN) | 2017-07-12 | — | — | EP | disclosed |
| EP-2708534-A1 | THIAZOLE COMPOUND AND PREPARATION METHOD AND USE THEREOF | Shanghai Puyi Chemical Co., Ltd. (CN) | 2014-03-19 | — | — | EP | disclosed |