Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12438096 | 0.87 | IGF1R (1.00) | IGF1RNTRK1 | |
| SCHEMBL11348597 | 0.83 | IGF1R (0.72) | IGF1RNTRK1 | |
| SCHEMBL27549041 | 0.83 | IGF1R (1.00) | IGF1RNTRK1 | |
| SCHEMBL11341232 | 0.82 | IGF1R (1.00) | IGF1RNTRK1 | |
| SCHEMBL11349378 | 0.82 | IGF1R (1.00) | IGF1RNTRK1 | |
| SCHEMBL11346698 | 0.82 | IGF1R (0.78) | IGF1RNTRK1 | |
| SCHEMBL2121935 | 0.82 | IGF1R (1.00) | IGF1RNTRK1 | |
| SCHEMBL11341602 | 0.81 | IGF1R (1.00) | IGF1RNTRK1 | |
| SCHEMBL11341250 | 0.81 | IGF1R (1.00) | IGF1RNTRK1 | |
| SCHEMBL11346204 | 0.80 | IGF1R (0.70) | IGF1RNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139484-B9 | METHODS OF TREATING CANCER USING PYRIDOPYRIMIDINONE INHIBITORS OF PI3K ALPHA | EXELIXIS INC (US) | 2014-06-11 | — | — | EP | disclosed |