Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GANAB | Q14697 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | MGAM | O43451 | 4/20 | 0.45 |
| ▸ | AGL | P35573 | 3/20 | 0.45 |
| ▸ | SI | P14410 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 3/20 | 0.45 |
| ▸ | PYGL | P06737 | 2/20 | 0.45 |
| ▸ | MAN1B1 | Q9UKM7 | 2/20 | 0.45 |
| ▸ | GBA2 | Q9HCG7 | 3/20 | 0.43 |
| ▸ | FUCA1 | P04066 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GBA1 | P04062 | 2/20 | 0.43 |
| ▸ | LCT | P09848 | 2/20 | 0.43 |
| ▸ | GBA3 | Q9H227 | 2/20 | 0.43 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.43 |
| ▸ | MAN2B2 | Q9Y2E5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18730394 | 1.00 | GANAB (0.69) | GANABGAAMGAMAGLSI | |
| SCHEMBL15598970 | 0.83 | GAA (0.68) | GANABGAAMGAMAGLSI | |
| SCHEMBL15599039 | 0.82 | GANAB (1.00) | GANABGAAMGAMAGLSI | |
| SCHEMBL29471360 | 0.82 | GANAB (1.00) | GANABGAAMGAMAGLSI | |
| SCHEMBL14119813 | 0.65 | GANAB (0.64) | GANABGAAMGAMAGLSI | |
| SCHEMBL6857345 | 0.65 | GANAB (0.64) | GANABGAAMGAMAGLSI | |
| SCHEMBL6857322 | 0.65 | GANAB (0.64) | GANABGAAMGAMAGLSI | |
| SCHEMBL8892109 | 0.62 | GANAB (0.54) | GANABGAAMGAMAGLSI | |
| Iminoribitol SCHEMBL981088 | 0.62 | — | — | |
| Iminoribitol SCHEMBL3365896 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170107180-A1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME CORP. | 2017-04-20 | — | — | US | disclosed |
| US-20170107180-A1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME CORP. | 2017-04-20 | — | — | US | disclosed |
| US-20150299122-A1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2015-10-22 | — | — | US | disclosed |
| US-20150299122-A1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2015-10-22 | — | — | US | disclosed |
| WO-2014032184-A1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2014-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299122-A1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | OGA, ENGASE, OGT | GANAB 56/4885GAA 6/4885MGAM 40/4885 |
| US-20170107180-A1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | OGA, ENGASE, OGT | GANAB 56/4885GAA 6/4885MGAM 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.