SCHEMBL15599299

SCHEMBL15599299

O=C(O)/C=C\C(=O)Oc1ccc2ccccc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.59
MEN1 O00255 1/20 0.59
MAPT P10636 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
PTPN7 P35236 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
ALDH1A1 P00352 1/20 0.49
HSD17B10 Q99714 1/20 0.49
FABP7 O15540 1/20 0.48
FABP3 P05413 1/20 0.48
PDGFRB P09619 1/20 0.47
PDGFRA P16234 1/20 0.47
TBXA2R P21731 1/20 0.47
PTGER4 P35408 1/20 0.47
PTGFR P43088 1/20 0.47
PTGER3 P43115 1/20 0.47
PTGER2 P43116 1/20 0.47
PTGDR Q13258 1/20 0.47
CYP1B1 Q16678 1/20 0.46
HCAR2 Q8TDS4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19335930 1.00 KMT2A (0.59) KMT2AMEN1MAPTTDP1PTPN7
SCHEMBL19333584 0.93 KMT2A (0.47) KMT2AMEN1MAPTTDP1L3MBTL1
SCHEMBL19333555 0.84 KMT2A (0.53) KMT2AMEN1MAPTTDP1PTPN7
SCHEMBL19333554 0.84 KMT2A (0.53) KMT2AMEN1MAPTTDP1PTPN7
SCHEMBL10798885 0.84 KMT2A (0.66) KMT2AMEN1MAPTTDP1L3MBTL1
SCHEMBL10798882 0.84 KMT2A (0.66) KMT2AMEN1MAPTTDP1L3MBTL1
SCHEMBL29293323 0.83 KMT2A (0.45) KMT2AMEN1MAPTTDP1PTPN7
SCHEMBL14989047 0.82 KMT2A (0.54) KMT2AMEN1MAPTTDP1PTPN7
SCHEMBL14989046 0.82 KMT2A (0.54) KMT2AMEN1MAPTTDP1PTPN7
SCHEMBL19721630 0.81 KMT2A (0.50) KMT2AMEN1MAPTTDP1PTPN7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2847809-B1 OLIGOMERIC ORGANIC LIGHT EMITTING DIODE(OLED)MATERIALS CONTAINING MULTIPLE CROSSLINKING FUNCTIONS LOMOX LTD (GB) 2017-12-20 EP disclosed
US-9761804-B2 Oligomeric organic light emitting diode (OLED) materials containing multiple crosslinking functions LOMOX LIMITED (GB) 2017-09-12 US disclosed
WO-2013167857-A1 OLIGOMERIC ORGANIC LIGHT EMITTING DIODE(OLED)MATERIALS CONTAINING MULTIPLE CROSSLINKING FUNCTIONS LOMOX LIMITED (GB) 2013-11-14 WO disclosed