Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 16/20 | 0.70 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.48 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.47 |
| ▸ | IL2 | P60568 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15599420 | 0.93 | ALK (0.69) | ALKTNIKMAPK1 | |
| SCHEMBL17787461 | 0.90 | ALK (0.70) | ALKTNIKMAP4K1IL2 | |
| Hydrochloric Acid SCHEMBL15556679 | 0.90 | ALK (0.70) | ALKTNIKMAP4K1IL2MAPK1 | |
| SCHEMBL15556394 | 0.90 | ALK (0.65) | ALKMAP4K1IL2MAPK1 | |
| SCHEMBL15556454 | 0.89 | ALK (0.69) | ALKTNIKMAPK1 | |
| SCHEMBL15556786 | 0.89 | ALK (0.68) | ALKTNIKMAP4K1 | |
| SCHEMBL15556947 | 0.88 | ALK (0.63) | ALKTNIKMAP4K1 | |
| SCHEMBL15599282 | 0.88 | ALK (0.67) | ALKTNIKMAP4K1IL2MAPK1 | |
| SCHEMBL15557273 | 0.87 | ALK (0.64) | ALKTNIKMAP4K1MAPK1 | |
| SCHEMBL15557244 | 0.87 | ALK (0.65) | ALKTNIKMAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014006554-A1 | 3-(PYRAZOLYL)-1H-PYRROLO[2,3-b]PYRIDINE DERIVATIVES AS KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-01-09 | — | — | WO | disclosed |