Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 17/20 | 0.72 |
| ▸ | PGR | P06401 | 10/20 | 0.72 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15599419 | 0.88 | AR (0.71) | ARPGRSLC2A1 | |
| SCHEMBL15421831 | 0.87 | AR (0.69) | ARPGRSLC2A1 | |
| SCHEMBL15421630 | 0.87 | AR (0.69) | ARPGRSLC2A1 | |
| SCHEMBL15421714 | 0.87 | AR (0.69) | ARPGRSLC2A1 | |
| SCHEMBL15549225 | 0.86 | AR (0.81) | ARPGRSLC2A1 | |
| SCHEMBL15421614 | 0.84 | AR (1.00) | ARPGRSLC2A1 | |
| SCHEMBL15421712 | 0.84 | AR (1.00) | ARPGRSLC2A1 | |
| SCHEMBL19649862 | 0.84 | AR (0.65) | ARPGR | |
| SCHEMBL19649806 | 0.84 | AR (0.65) | ARPGR | |
| SCHEMBL15421613 | 0.84 | AR (1.00) | ARPGRSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014013309-A1 | INDOLECARBONITRILES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2014-01-23 | — | — | WO | disclosed |