Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RGS12 | O14924 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15600668 | 0.90 | MEN1 (0.46) | MEN1RGS12USP2POLBMAPT | |
| SCHEMBL17522974 | 0.87 | MEN1 (0.46) | MEN1RGS12USP2POLBMAPT | |
| SCHEMBL17525438 | 0.82 | CYP1B1 (0.51) | MEN1POLBMAPTKMT2AHDAC1 | |
| SCHEMBL7524308 | 0.82 | KMT2A (0.69) | MEN1RGS12USP2POLBMAPT | |
| SCHEMBL15600669 | 0.82 | KDM4E (0.51) | MEN1USP2POLBMAPTMAPK1 | |
| SCHEMBL15600753 | 0.81 | MAPT (0.42) | MEN1RGS12USP2POLBMAPT | |
| Acetic Acid SCHEMBL29387147 | 0.80 | MEN1 (0.53) | MEN1RGS12USP2POLBMAPT | |
| SCHEMBL22181166 | 0.80 | MEN1 (0.58) | MEN1RGS12USP2POLBMAPT | |
| SCHEMBL29387419 | 0.79 | MEN1 (0.57) | MEN1RGS12USP2POLBMAPT | |
| SCHEMBL22164719 | 0.79 | MEN1 (0.57) | MEN1RGS12USP2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014022807-A2 | COMPOSITIONS AND METHODS OF USING THE COMPOSITIONS FOR PLAQUE SOFTENING | ALUMEND, LLC (US) | 2014-02-06 | — | — | WO | disclosed |