⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15602021 | 1.00 | — | — | |
| SCHEMBL11640412 | 1.00 | — | — | |
| SCHEMBL15602061 | 1.00 | — | — | |
| SCHEMBL24298249 | 0.77 | — | — | |
| SCHEMBL16169057 | 0.77 | SLC22A2 (0.33) | — | |
| SCHEMBL15540955 | 0.73 | — | — | |
| SCHEMBL15540501 | 0.73 | — | — | |
| SCHEMBL15540928 | 0.73 | — | — | |
| SCHEMBL15541711 | 0.73 | — | — | |
| SCHEMBL26981812 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867225-B1 | PYRROLIDINE DERIVATIVES AND THEIR USE AS COMPLEMENT PATHWAY MODULATORS | NOVARTIS AG (CH) | 2017-08-09 | — | — | EP | disclosed |
| WO-2014002054-A1 | PYRROLIDINE DERIVATIVES AND THEIR USE AS COMPLEMENT PATHWAY MODULATORS | NOVARTIS AG (CH) | 2014-01-03 | — | — | WO | disclosed |