Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15612755 | 0.93 | HDAC1 (0.70) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL16558080 | 0.88 | HDAC1 (0.64) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL28247407 | 0.88 | HDAC1 (0.63) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL5773620 | 0.86 | HDAC1 (0.61) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL15612925 | 0.85 | HDAC1 (0.70) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL15528574 | 0.83 | HDAC1 (0.65) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL15529339 | 0.82 | HDAC6 (0.60) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL15610731 | 0.81 | HDAC1 (0.59) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL16558088 | 0.81 | HDAC1 (0.75) | HDAC1HDAC6HDAC8HDAC3HDAC4 | |
| SCHEMBL15612833 | 0.81 | HDAC1 (0.71) | HDAC1HDAC6HDAC8HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013166013-A1 | ROR MODULATORS AND THEIR USES | GAWECO ANDERSON (US) | 2013-11-07 | — | — | WO | disclosed |