Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL656963 | 0.96 | CHRNA7 (0.33) | — | |
| SCHEMBL18960 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL28596120 | 0.92 | CHRNA7 (0.32) | — | |
| SCHEMBL9349701 | 0.92 | CHRNA7 (0.32) | — | |
| SCHEMBL28421467 | 0.92 | — | — | |
| SCHEMBL9232705 | 0.92 | — | — | |
| Water SCHEMBL1542414 | 0.92 | CHRNA7 (0.32) | — | |
| Fluoride SCHEMBL2112417 | 0.92 | CHRNA7 (0.32) | — | |
| SCHEMBL538360 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL2962579 | 0.92 | CHRNA7 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376489-A1 | Alkaloid aminoester derivatives and medicinal composition thereof | Chiesi Farmaceutici S.p.A. (IT) | 2011-10-19 | — | — | EP | claimed |
| WO-2010072338-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-07-01 | — | — | WO | claimed |
| EP-1740177-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2007-01-10 | — | — | EP | claimed |
| WO-2005104745-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-11-10 | — | — | WO | claimed |
| US-12396986-B2 | Combinations of a muscarinic receptor antagonist and a β-2 adrenoreceptor agonist | GLAXO GROUP LIMITED (GB) | 2025-08-26 | — | — | US | disclosed |
| EP-3982923-B1 | CONTINUOUS PROCESS FOR THE PREPARATION OF ANTICHOLINERGIC DRUGS | HOVIONE SCIENTIA LTD (IE) | 2024-05-15 | — | — | EP | disclosed |
| US-20240041846-A1 | COMBINATIONS OF A MUSCARINIC RECEPTOR ANTAGONIST AND A BETA-2 ADRENORECEPTOR AGONIST | GLAXO GROUP LIMITED (GB) | 2024-02-08 | — | — | US | disclosed |
| US-20240025890-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES INC (US) | 2024-01-25 | — | — | US | disclosed |
| US-11814376-B2 | Hepatitis b core protein modulators | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| CN-116194114-A | Cathepsin inhibitors for preventing or treating viral infections | 葛兰素史密斯克莱知识产权发展有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-110090308-B | Method for preparing conjugate | 四川科伦博泰生物医药股份有限公司 | 2023-03-24 | — | — | CN | disclosed |
| US-20230044112-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-02-09 | — | — | US | disclosed |
| US-20050288266-A1 | Combinations comprising antimuscarinic agents and corticosteroids | GRAS ESCARDO JORDI | 2005-12-29 | — | — | US | disclosed |
| WO-2005115462-A1 | COMBINATIONS COMPRISING ANTIMUSCARINIC AGENTS AND PDE4 INHIBITORS | ALMIRALL PRODESFARMA S.A. (ES) | 2005-12-08 | — | — | WO | disclosed |
| WO-2005115463-A1 | COMBINATIONS COMPRISING ANTIMUSCARINIC AGENTS AND BETA-ADRENERGIC AGONISTS | ALMIRALL PRODESFARMA S.A. (ES) | 2005-12-08 | — | — | WO | disclosed |
| US-20050267078-A1 | Combinations comprising antimuscarinic agents and beta-adrenergic agonists | GRAS ESCARDO JORDI | 2005-12-01 | — | — | US | disclosed |
| US-20050267135-A1 | Combinations comprising antimuscarinic agents and PDE4 inhibitors | ESCARDO JORDI G | 2005-12-01 | — | — | US | disclosed |
| WO-2005112644-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-12-01 | — | — | WO | disclosed |
| WO-2005090342-A1 | NEW QUATERNIZED QUINUCLIDINE ESTERS | ALMIRALL PRODESFARMA, SA (ES) | 2005-09-29 | — | — | WO | disclosed |
| US-20050020660-A1 | Quinuclidine derivatives processes for preparing them and their uses as m2 and/or m3 muscarinic receptor inhibitors | UCB, S.A. (BE) | 2005-01-27 | — | — | US | disclosed |