Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 5/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15613739 | 0.92 | BTK (0.35) | BTKGRM2ABL1SRC | |
| SCHEMBL15613686 | 0.86 | BTK (0.47) | BTKSCN9ATGFBR1TGFBR2GRM2 | |
| SCHEMBL15613497 | 0.84 | BTK (0.34) | BTKTGFBR1GRM2 | |
| SCHEMBL15613591 | 0.83 | SRC (0.46) | BTKABL1SRC | |
| SCHEMBL15613645 | 0.82 | BTK (0.44) | BTKSCN9A | |
| SCHEMBL15613769 | 0.81 | KCNH2 (0.36) | BTKTGFBR1TGFBR2 | |
| SCHEMBL15613667 | 0.81 | BTK (0.38) | BTK | |
| SCHEMBL15613530 | 0.79 | SRC (0.46) | BTKABL1SRC | |
| SCHEMBL15613741 | 0.78 | BTK (0.48) | BTKGRM2ABL1SRC | |
| SCHEMBL15613635 | 0.76 | BTK (0.41) | BTKGRM2ABL1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796716-B2 | Selective inhibitors of Tec and Src protein kinase families | PHARMASCIENCE, INC. (CA) | 2017-10-24 | — | — | US | disclosed |
| US-20150191473-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE, INC. (CA) | 2015-07-09 | — | — | US | disclosed |
| WO-2013177668-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE, INC. (CA) | 2013-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191473-A1 | PROTEIN KINASE INHIBITORS | TEC, SRC, LCK | BTK 10/4885SCN9A 4137/4885TGFBR1 3154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.