Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 8/20 | 0.60 |
| ▸ | LCK | P06239 | 3/20 | 0.60 |
| ▸ | LYN | P07948 | 1/20 | 0.60 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.53 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 12/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.51 |
| ▸ | SRC | P12931 | 11/20 | 0.51 |
| ▸ | KDR | P35968 | 11/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 11/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.51 |
| ▸ | PRKDC | P78527 | 11/20 | 0.51 |
| ▸ | ABL1 | P00519 | 10/20 | 0.51 |
| ▸ | HCK | P08631 | 10/20 | 0.51 |
| ▸ | MTOR | P42345 | 10/20 | 0.51 |
| ▸ | EPHB4 | P54760 | 10/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 9/20 | 0.51 |
| ▸ | TEK | Q02763 | 1/20 | 0.50 |
| ▸ | ITK | Q08881 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15613683 | 0.94 | BTK (0.59) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613706 | 0.92 | BTK (0.65) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613671 | 0.88 | BTK (0.51) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613542 | 0.86 | BTK (0.56) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613534 | 0.86 | BTK (0.48) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL16886156 | 0.84 | BTK (0.60) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL16886129 | 0.81 | BTK (0.49) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613659 | 0.81 | BTK (0.59) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613529 | 0.80 | BTK (0.61) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL25466299 | 0.80 | BTK (0.80) | BTKLCKLYNNUDT14NUDT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013177668-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE, INC. (CA) | 2013-12-05 | — | — | WO | disclosed |