Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 16/20 | 0.49 |
| ▸ | LCK | P06239 | 7/20 | 0.49 |
| ▸ | LYN | P07948 | 2/20 | 0.49 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.48 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 3/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 7/20 | 0.45 |
| ▸ | ITK | Q08881 | 3/20 | 0.45 |
| ▸ | IGF1R | P08069 | 2/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | CSK | P41240 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | YES1 | P07947 | 1/20 | 0.42 |
| ▸ | HCK | P08631 | 1/20 | 0.42 |
| ▸ | FGR | P09769 | 1/20 | 0.42 |
| ▸ | FER | P16591 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15613711 | 0.87 | BTK (0.61) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613514 | 0.85 | BTK (0.50) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613681 | 0.84 | BTK (0.52) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613502 | 0.84 | BTK (0.49) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613520 | 0.83 | BTK (0.53) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613499 | 0.81 | BTK (0.47) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613512 | 0.80 | BTK (0.61) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL16886168 | 0.80 | BTK (0.53) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613753 | 0.80 | BTK (0.48) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613550 | 0.80 | BTK (0.55) | BTKLCKLYNNUDT14NUDT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013177668-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE, INC. (CA) | 2013-12-05 | — | — | WO | disclosed |