Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.61 |
| ▸ | LCK | P06239 | 3/20 | 0.61 |
| ▸ | LYN | P07948 | 1/20 | 0.61 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.52 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | TEK | Q02763 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | ITK | Q08881 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15613695 | 0.85 | BTK (0.79) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613524 | 0.85 | BTK (0.66) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613639 | 0.82 | BTK (0.68) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613546 | 0.82 | BTK (0.79) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL6435597 | 0.82 | BTK (0.75) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL16886149 | 0.81 | BTK (0.69) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613616 | 0.79 | BTK (0.66) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613473 | 0.79 | BTK (0.56) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL15613527 | 0.79 | BTK (0.68) | BTKLCKLYNNUDT14NUDT5 | |
| SCHEMBL24041322 | 0.78 | BTK (0.78) | BTKLCKLYNNUDT14NUDT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013177668-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE, INC. (CA) | 2013-12-05 | — | — | WO | disclosed |