Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.70 |
| ▸ | PGR | P06401 | 1/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.70 |
| ▸ | HTR1A | P08908 | 1/20 | 0.70 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | DRD1 | P21728 | 1/20 | 0.70 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | PDE4A | P27815 | 1/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.70 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.70 |
| ▸ | DRD3 | P35462 | 1/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.69 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12279970 | 0.91 | ESR1 (0.68) | ESR1PGRCHRM2HTR1AADRA2A | |
| SCHEMBL21980373 | 0.89 | ESR1 (0.87) | ESR1PGRCHRM2HTR1AADRA2A | |
| SCHEMBL15426058 | 0.88 | ESR1 (0.63) | ESR1PGRCHRM2HTR1AADRA2A | |
| SCHEMBL15426050 | 0.87 | ESR1 (0.62) | ESR1PGRCHRM2HTR1AADRA2A | |
| SCHEMBL16363118 | 0.85 | ESR1 (0.51) | ESR1PGRCHRM2HTR1AADRA2A | |
| SCHEMBL22039130 | 0.84 | ESR1 (0.65) | ESR1PGRCHRM2HTR1AADRA2A | |
| SCHEMBL15426051 | 0.84 | ESR1 (0.58) | ESR1PGRCHRM2HTR1AADRA2A | |
| SCHEMBL2565788 | 0.84 | ESR1 (0.78) | ESR1PGRCHRM2HTR1AADRA2A | |
| SCHEMBL15201325 | 0.83 | ESR1 (0.77) | ESR1PGRCHRM2HTR1AADRA2A | |
| Dronedarone SCHEMBL110363 | 0.82 | ESR1 (1.00) | ESR1PGRCHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9193703-B2 | Process for preparation of dronedarone by mesylation | SANOFI (FR) | 2015-11-24 | — | — | US | disclosed |
| US-20140081035-A1 | PROCESS FOR PREPARATION OF DRONEDARONE BY MESYLATION | SANOFI (FR) | 2014-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140081035-A1 | PROCESS FOR PREPARATION OF DRONEDARONE BY MESYLATION | CYP2B6, CYP2D6, CYP7A1 | ESR1 4411/4885PGR 2550/4885CHRM2 2733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.