Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.53 |
| ▸ | MMP3 | P08254 | 5/20 | 0.51 |
| ▸ | MMP2 | P08253 | 6/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15615843 | 1.00 | HDAC1 (0.53) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL15615844 | 1.00 | HDAC1 (0.53) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL15615845 | 0.97 | HDAC1 (0.56) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL15615842 | 0.97 | HDAC1 (0.56) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL15615841 | 0.97 | HDAC1 (0.56) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL16848628 | 0.95 | HDAC1 (0.45) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL16848626 | 0.95 | HDAC1 (0.45) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL16848624 | 0.95 | HDAC1 (0.45) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL17860078 | 0.94 | HDAC1 (0.43) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL17971135 | 0.94 | HDAC1 (0.43) | HDAC1HDAC2MMP3MMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2870217-B1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-07-20 | — | — | EP | disclosed |
| US-20150175883-A1 | Bimesogenic Compounds and Mesogenic Media | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20150175883-A1 | Bimesogenic Compounds and Mesogenic Media | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| WO-2014005672-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2014-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175883-A1 | Bimesogenic Compounds and Mesogenic Media | SP1, FOXM1, S100A11 | HDAC1 2242/4885HDAC2 3725/4885MMP3 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.