Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 11/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 11/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13542726 | 0.84 | GRM1 (0.43) | PDK4GRM5GRM1NAMPTESR2 | |
| SCHEMBL2950438 | 0.82 | GRM1 (0.46) | PDK4GRM5GRM1NAMPTESR2 | |
| SCHEMBL29233999 | 0.82 | PDK4 (0.46) | PDK4GRM5GRM1NAMPTESR2 | |
| SCHEMBL18293252 | 0.81 | PDK4 (0.48) | PDK4GRM5GRM1NAMPTESR2 | |
| SCHEMBL10225837 | 0.81 | GRM5 (0.46) | PDK4GRM5GRM1NAMPTESR2 | |
| SCHEMBL20841532 | 0.81 | GRM1 (0.46) | PDK4GRM5GRM1NAMPTESR2 | |
| SCHEMBL212403 | 0.80 | PDK4 (0.46) | PDK4GRM5GRM1NAMPTESR2 | |
| SCHEMBL5078071 | 0.80 | PDK4 (0.43) | PDK4GRM5GRM1NAMPTESR2 | |
| SCHEMBL18068367 | 0.79 | PDK4 (0.46) | PDK4GRM5GRM1NAMPTESR2 | |
| SCHEMBL20459306 | 0.79 | PDK4 (0.49) | PDK4GRM5GRM1NAMPTESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014026243-A1 | VEGFR3 INHIBITORS | CANCER THERAPEUTICS CRC PTY LIMITED (AU) | 2014-02-20 | — | — | WO | disclosed |