Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 13/20 | 0.62 |
| ▸ | TUBB4A | P04350 | 12/20 | 0.55 |
| ▸ | TUBB | P07437 | 12/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 12/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 12/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 12/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 12/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 12/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 12/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 12/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 12/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 12/20 | 0.55 |
| ▸ | TUBA1C | Q9BQE3 | 12/20 | 0.55 |
| ▸ | TUBB6 | Q9BUF5 | 12/20 | 0.55 |
| ▸ | TUBB2B | Q9BVA1 | 12/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1562909 | 0.90 | TUBB1 (0.59) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1562296 | 0.86 | TUBB1 (0.61) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1562284 | 0.85 | TUBB1 (0.62) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1563066 | 0.82 | TUBB1 (0.60) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17417699 | 0.81 | MAPT (0.53) | TUBB1 | |
| SCHEMBL1563089 | 0.80 | TUBB1 (0.67) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL21366271 | 0.78 | TUBB1 (0.73) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1562348 | 0.78 | TUBB1 (0.72) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL565514 | 0.76 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1562294 | 0.76 | TUBB1 (0.77) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506960-B1 | Indole compounds as inhibitors of tubulin polymerisation for the treatment of angiogenesis-related disorders | NAT HEALTH RESEARCH INSTITUTES (TW) | 2011-04-06 | — | — | EP | claimed |