Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 20/20 | 0.82 |
| ▸ | MTOR | P42345 | 5/20 | 0.82 |
| ▸ | PIK3R1 | P27986 | 11/20 | 0.63 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5559466 | 0.90 | PIK3CA (1.00) | PIK3CAMTORPIK3R1PIK3CDPIK3CB | |
| SCHEMBL26078997 | 0.90 | PIK3CA (0.84) | PIK3CAMTORPIK3R1PIK3CDPIK3CB | |
| SCHEMBL15603034 | 0.89 | PIK3CA (0.78) | PIK3CAMTORPIK3R1PIK3CDPIK3CB | |
| Lithium Ion SCHEMBL30366291 | 0.88 | PIK3CA (0.81) | PIK3CAMTORPIK3R1PIK3CDPIK3CB | |
| SCHEMBL26078996 | 0.84 | PIK3CA (0.74) | PIK3CAMTORPIK3R1PIK3CDPIK3CB | |
| SCHEMBL5559887 | 0.84 | PIK3CA (1.00) | PIK3CAMTORPIK3R1PIK3CDPIK3CB | |
| SCHEMBL15603030 | 0.83 | PIK3CA (0.69) | PIK3CAMTORPIK3R1PIK3CDPIK3CB | |
| SCHEMBL15603170 | 0.83 | PIK3CA (1.00) | PIK3CAMTORPIK3R1PIK3CDPIK3CB | |
| SCHEMBL30366589 | 0.83 | PIK3CA (0.66) | PIK3CAMTORPIK3R1PIK3CDPIK3CB | |
| SCHEMBL15602962 | 0.82 | PIK3CA (1.00) | PIK3CAMTORPIK3R1PIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419429-B1 | IMIDAZOPYRAZINES AS INHIBITORS OF PROTEIN KINASES | CT NAC INVESTIGACIONES ONCOLOGICAS CNIO (ES) | 2014-03-26 | — | — | EP | disclosed |