Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | WDR91 | A4D1P6 | 3/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 3/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.31 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3823383 | 0.95 | WDR91 (0.35) | WDR91ABL1RORCPRKAG1PRKAA1 | |
| SCHEMBL3823380 | 0.95 | WDR91 (0.35) | WDR91ABL1RORCPRKAG1PRKAA1 | |
| Hydrochloric Acid SCHEMBL3386424 | 0.94 | WDR91 (0.34) | WDR91ABL1RORCPRKAG1PRKAA1 | |
| SCHEMBL13327498 | 0.90 | HDAC3 (0.34) | SMN1; SMN2WDR91MAPTLMNAL3MBTL1 | |
| SCHEMBL18774368 | 0.86 | PHGDH (0.34) | SMN1; SMN2WDR91RORCOPRD1PHGDH | |
| SCHEMBL18774306 | 0.86 | HDAC3 (0.32) | SMN1; SMN2HTTMAPTLMNAL3MBTL1 | |
| SCHEMBL18774288 | 0.86 | — | — | |
| SCHEMBL13327503 | 0.83 | HDAC3 (0.31) | — | |
| SCHEMBL13799703 | 0.82 | — | — | |
| SCHEMBL18774277 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2053094-B1 | Composition for dyeing keratinous fibres comprising at least one direct dye with disulphur/thiol function and at least one polymer with thiol function and method using the composition | OREAL (FR) | 2014-03-26 | — | — | EP | disclosed |