Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | PLEC | Q15149 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 11/20 | 0.48 |
| ▸ | CA1 | P00915 | 9/20 | 0.47 |
| ▸ | CA2 | P00918 | 9/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | CDC25C | P30307 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25861609 | 0.86 | USP2 (0.62) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL31344171 | 0.81 | USP2 (0.60) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL8930410 | 0.81 | MEN1 (0.74) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL13052196 | 0.81 | USP2 (0.56) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL18155821 | 0.80 | USP2 (0.72) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL15143773 | 0.79 | USP2 (0.53) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL1437042 | 0.78 | USP2 (0.78) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL19423916 | 0.78 | USP2 (0.73) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL7824274 | 0.78 | USP2 (0.77) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL14768993 | 0.78 | USP2 (0.63) | USP2MEN1KMT2APOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252595-B1 | OXIM DERIVATIVES AS HSP90 INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2014-03-26 | — | — | EP | disclosed |