Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.32 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13078850 | 0.88 | MEN1 (0.37) | ALDH1A1MEN1KMT2ANR1H2PREP | |
| SCHEMBL501213 | 0.88 | MEN1 (0.37) | ALDH1A1MEN1KMT2ANR1H2PREP | |
| SCHEMBL3574137 | 0.88 | MEN1 (0.37) | ALDH1A1MEN1KMT2ANR1H2PREP | |
| SCHEMBL18610757 | 0.87 | NR1H2 (0.37) | ALDH1A1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL15247679 | 0.84 | PREP (0.38) | SMN1; SMN2NR1H2PREP | |
| SCHEMBL4304970 | 0.81 | PREP (0.36) | NR1H2PREP | |
| SCHEMBL15087428 | 0.81 | PREP (0.36) | NR1H2PREP | |
| SCHEMBL18610756 | 0.79 | GBA2 (0.34) | ALDH1A1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL13427814 | 0.79 | GBA2 (0.40) | ALDH1A1L3MBTL1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL24113489 | 0.79 | EPHX1 (0.38) | NR1H2PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014045263-A2 | PROCESS FOR PREPARATION OF INTERMEDIATES OF TELAPREVIR | DR. REDDY'S LABORATORIES LIMITED (IN) | 2014-03-27 | — | — | WO | disclosed |