⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL28224028 | 0.97 | — | — | |
| SCHEMBL4584646 | 0.80 | — | — | |
| SCHEMBL82304 | 0.80 | — | — | |
| Ammonia Solution, Strong SCHEMBL27508580 | 0.77 | — | — | |
| SCHEMBL31520440 | 0.77 | UHRF1 (0.41) | — | |
| Ethoxycarbonyl Group SCHEMBL27894074 | 0.77 | POLB (0.34) | — | |
| SCHEMBL10021907 | 0.69 | CCR1 (0.41) | — | |
| SCHEMBL5666185 | 0.67 | UHRF1 (0.35) | — | |
| SCHEMBL16848019 | 0.65 | — | — | |
| SCHEMBL19053655 | 0.65 | NPC1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119009136-A | Pyrazinyl eutectic electrolyte with wide electrochemical stability window, and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2024-11-22 | — | — | CN | claimed |
| JP-6345741-A | — | — | None | — | — | JP | disclosed |
| EP-4647429-A1 | PYRIDAZINONE HETEROCYCLIC COMPOUND MYOSIN II INHIBITOR AND USE THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2025-11-12 | — | — | EP | disclosed |
| US-12233062-B2 | Heterocyclic derivatives useful as SHP2 inhibitors | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2025-02-25 | — | — | US | disclosed |
| CN-119009136-A | Pyrazinyl eutectic electrolyte with wide electrochemical stability window, and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2024-11-22 | — | — | CN | disclosed |
| US-20240285617-A1 | NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2024-08-29 | — | — | US | disclosed |
| US-20240245681-A1 | HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS | JACOBO PHARMACEUTICATS CO LTD (CN) | 2024-07-25 | — | — | US | disclosed |
| WO-2024146559-A1 | PYRIDAZINONE HETEROCYCLIC COMPOUND MYOSIN II INHIBITOR AND USE THEREOF | 西藏海思科制药有限公司 | 2024-07-11 | — | — | WO | disclosed |
| US-20240208992-A1 | MACROCYCLES AS CFTR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-27 | — | — | US | disclosed |
| US-20240116921-A1 | LACTAM (HETERO)ARYLFUSEDPYRIMIDINE DERIVATIVES AS INHIBITORS OF ERBB2 | ENLIVEN INC. | 2024-04-11 | — | — | US | disclosed |
| US-5618821-A | VIRICIDES, PICORNAVIRUS | SANOFI, S.A. (FR) | 1997-04-08 | — | — | US | disclosed |
| WO-1995031438-A1 | THERAPEUTIC PHENOXYALKYLHETEROCYCLES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |
| EP-0477829-B1 | Microbiological process for the preparation of hydroxylated heterocyclic compounds | LONZA AG (CH) | 1995-06-28 | — | — | EP | disclosed |
| JP-H06345741-A | PRODUCTION OF PYRAZINE DERIVATIVE | KANEBO LTD | 1994-12-20 | — | — | JP | disclosed |
| US-5284767-A | Pyrazines or quinoxalines as the sole carbon, nitrogen and energy source | LONZA LTD. (CH) | 1994-02-08 | — | — | US | disclosed |
| US-5266482-A | Biosynthesis | LONZA LTD. (CH) | 1993-11-30 | — | — | US | disclosed |
| US-5229278-A | Hydroxylating a pyrazine or quinoxaline with a microorganism Rhodococcus or Arthrobacter | LONZA LTD. (CH) | 1993-07-20 | — | — | US | disclosed |
| US-5173412-A | Converted with microorganism Agrobacterium | LONZA, LTD. (CH) | 1992-12-22 | — | — | US | disclosed |
| EP-0484908-A2 | Microbiological process for the preparation of hydroxylated Pyrazinederivatives | LONZA A.G. (CH) | 1992-05-13 | — | — | EP | disclosed |
| EP-0477829-A2 | Microbiological process for the preparation of hydroxylated heterocyclic compounds | LONZA AG (CH) | 1992-04-01 | — | — | EP | disclosed |