Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 18/20 | 0.63 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15636586 | 1.00 | CTSA (0.63) | CTSAWDR5CYP26A1 | |
| SCHEMBL15636782 | 0.91 | CTSA (0.59) | CTSACYP26A1 | |
| SCHEMBL15635928 | 0.90 | CTSA (0.62) | CTSA | |
| SCHEMBL15636796 | 0.90 | CTSA (0.62) | CTSA | |
| SCHEMBL15635942 | 0.89 | CTSA (0.59) | CTSAWDR5CYP26A1 | |
| SCHEMBL15635374 | 0.89 | CTSA (0.56) | CTSACYP26A1 | |
| SCHEMBL15636681 | 0.88 | CTSA (0.61) | CTSACYP26A1 | |
| SCHEMBL15635996 | 0.88 | CTSA (0.60) | CTSACYP26A1 | |
| SCHEMBL15636318 | 0.88 | CTSA (0.60) | CTSACYP26A1 | |
| SCHEMBL15636507 | 0.87 | CTSA (0.57) | CTSAWDR5CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014053533-A1 | USE OF SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AS PHARMACEUTICALS FOR PREVENTION/TREATMENT OF ATRIAL FIBRILLATION | SANOFI (FR) | 2014-04-10 | — | — | WO | disclosed |